Patricia Ohana Selected Research

Liposomes (Liposome)

1/2021	Liposome co-encapsulation of anti-cancer agents for pharmacological optimization of nanomedicine-based combination chemotherapy.
10/2020	Pharmacokinetics of mitomycin-c lipidic prodrug entrapped in liposomes and clinical correlations in metastatic colorectal cancer patients.
1/2020	Development of Promitil®, a lipidic prodrug of mitomycin c in PEGylated liposomes: From bench to bedside.
1/2018	Targeting of folate-conjugated liposomes with co-entrapped drugs to prostate cancer cells via prostate-specific membrane antigen (PSMA).
1/2018	Chemo-Radiotherapy of Oligometastases of Colorectal Cancer With Pegylated Liposomal Mitomycin-C Prodrug (Promitil): Mechanistic Basis and Preliminary Clinical Experience.
3/2016	Targeting of pegylated liposomal mitomycin-C prodrug to the folate receptor of cancer cells: Intracellular activation and enhanced cytotoxicity.

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Patricia Ohana Research Topics

Disease

18	Neoplasms (Cancer) 01/2022 - 06/2004
4	Ascites 03/2016 - 08/2009
3	Colorectal Neoplasms (Colorectal Cancer) 10/2020 - 11/2016
3	Neoplasm Metastasis (Metastasis) 12/2011 - 06/2004
3	Ovarian Neoplasms (Ovarian Cancer) 09/2010 - 08/2009
3	Urinary Bladder Neoplasms (Bladder Cancer) 12/2008 - 04/2002
2	Carcinoma (Carcinomatosis) 10/2020 - 01/2011
1	Prostatic Neoplasms (Prostate Cancer) 01/2018
1	Lymphoma (Lymphomas) 03/2016
1	Carcinogenesis 02/2013
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2012
1	Colonic Neoplasms (Colon Cancer) 12/2011
1	Lung Neoplasms (Lung Cancer) 01/2011
1	Hypoxia (Hypoxemia) 04/2010
1	Hepatocellular Carcinoma (Hepatoma) 06/2004

Drug/Important Bio-Agent (IBA)

7	ProdrugsIBA 01/2022 - 10/2015
7	Mitomycin (Mitomycin-C)FDA LinkGeneric 01/2022 - 10/2015
6	Liposomes (Liposome)IBA 01/2021 - 03/2016
6	Diphtheria ToxinIBA 02/2013 - 03/2005
4	Pharmaceutical PreparationsIBA 01/2022 - 01/2011
4	H19 long non-coding RNAIBA 02/2013 - 06/2004
3	DNA (Deoxyribonucleic Acid)IBA 01/2011 - 03/2005
2	Folic Acid (Vitamin M)FDA LinkGeneric 01/2018 - 03/2016
2	Sulfhydryl Compounds (Thiols)IBA 01/2018 - 03/2016
2	Proteins (Proteins, Gene)FDA Link 02/2013 - 06/2004
2	A-Form DNA (A-DNA)IBA 02/2013 - 01/2012
2	diphtheria toxin fragment AIBA 01/2012 - 07/2010
2	RNA (Ribonucleic Acid)IBA 09/2010 - 06/2004
1	1-dodecylpyridoxal (PLD)IBA 01/2021
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2018
1	AntigensIBA 01/2018
1	LipidsIBA 11/2016
1	Anti-Bacterial Agents (Antibiotics)IBA 03/2016
1	Reducing AgentsIBA 03/2016
1	Gemcitabine FDA Link 01/2012
1	PolyethyleneimineIBA 01/2011
1	Phenobarbital (Luminal)FDA Link 01/2011
1	CytokinesIBA 09/2010
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2010
1	Tumor Biomarkers (Tumor Markers)IBA 12/2008
1	4-O-carboxymethylascochlorinIBA 12/2008
1	CarcinogensIBA 07/2006
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2005
1	Insulin (Novolin)FDA Link 03/2005

Therapy/Procedure

10	Therapeutics 01/2022 - 03/2005
2	Drug Therapy (Chemotherapy) 01/2021 - 01/2020
1	Combination Drug Therapy (Combination Chemotherapy) 01/2021
1	Radiotherapy 01/2018
1	Chemoradiotherapy 11/2016
1	Injections 12/2011
1	Intravenous Injections 01/2011
1	Intravesical Administration 12/2008
1	Subcutaneous Injections 04/2002